The concomitant use of benzodiazepines and opioids increases the danger of respiratory despair because of actions at various receptor web pages inside the CNS that Manage respiration. Benzodiazepines interact at GABAA sites, and opioids interact primarily at mu receptors. When benzodiazepines and opioids are mixed, the likely for benzodiazepines to https://caretechpharmacy.com