A comprehensive literature evaluate of scientific studies concerning 1995 and 2018 was conducted using the electronic databases PubMed and EBSCO Host. Searches had been carried out working with the next phrases: total knee arthroplasty (TKA); cyclooxygenase-2 inhibitors; bracing; Bodily therapy; weightloss; knee; treatment; therapeutics; OA; intra-articular injection; hyaluronic acid;... https://www.theorthopaedicandpainpractice.com/non-surgical-treatments-for-knee-joint-pain/